NiceProt View of SWISS-PROT: Q05925

[General] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

General information about the entry
Entry name	HME1_HUMAN
Primary accession number	Q05925
Secondary accession number(s)	None
Entered in SWISS-PROT in	Release 28, February 1994
Sequence was last modified in	Release 28, February 1994
Annotations were last modified in	Release 28, February 1994
Name and orig in of the protein
Protein name	HOMEOBOX PROTEIN ENGRAILED-1
Synonym(s)	HU-EN-1
Gene name(s)	EN1
From	Homo sapiens (Human)
Taxonomy	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
References
[1] SEQUENCE FROM N.A. MEDLINE; 93185339. [NCBI, ExPASy, Israel, Japan] Logan C., Hanks M.C., Noble-Topham S., Nallainathan D., Provart N.J., Joyner A.L.; "Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regions."; Dev. Genet. 13:345-358(1992).
Comments
SUBCELLULAR LOCATION: NUCLEAR. SIMILARITY: BELONGS TO THE ENGRAILED FAMILY OF HOMEOBOX PROTEINS.
Copyright
This SWISS-PROT entry is copyright. It is produced through a collaboration between the Swiss Institute of Bioinformatics and the EMBL outstation - the European Bioinformatics Institute. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified and this statement is not removed. Usage by and for commercial entities requires a license agreement (See http://www.isb-sib.ch/announce/ or send an email to license@isb-sib.ch).
Cross-references
EMBL L12698; AAA53501.1; -. [EMBL / GenBank / DDBJ] [CoDingSequence] L12699; AAA53502.1; -. [EMBL / GenBank / DDBJ] [CoDingSequence] HSSP P02836; 1ENH. [HSSP ENTRY / SWISS-3DIMAGE / PDB] TRANSFAC T02015; -. MIM 131290; -. GeneCards EN1. PRINTS PR00024; HOMEOBOX. PR00026; ENGRAILED. PROSITE PS00027; HOMEOBOX_1; 1. PS50071; HOMEOBOX_2; 1. PS00033; ENGRAILED; 1. PFAM PF00046; homeobox; 1. PRODOM [Domain structure / List of seq. sharing at least 1 domain] BLOCKS Q05925. DOMO Q05925. PROTOMAP Q05925. PRESAGE Q05925. SWISS-2DPAGE GET REGION ON 2D PAGE.
Keywords
Homeobox; DNA-binding; Developmental protein; Nuclear protein.
Features
DOMAIN 199 218 POLY-ALA. DOMAIN 224 231 POLY-GLY. DNA_BIND 302 361 HOMEOBOX. FT table viewer
Sequence information
Length: 391 AA Molecular weight: 40044 Da CRC64: 30DA29BF0995956F [This is a checksum on the sequence]
10 20 30 40 50 60 | | | | | | MEEQQPEPKS QRDSALGGAA AATPGGLSLS LSPGASGSSG SGSDGDSVPV SPQPAPPSPP 70 80 90 100 110 120 | | | | | | AAPCLPPLAH HPHLPPHPPP PPPQHLAAPA HQPQPAAQLH RTTNFFIDNI LRPDFGCKKE 130 140 150 160 170 180 | | | | | | QPPPQLLVAA AARGGAGGGG RVERDRGQTA AGRDPVHPLG TRAPGAASLL CAPDANCGPP 190 200 210 220 230 240 | | | | | | DGSQPAAAGA GASKAGNPAA AAAAAAAAVA AAAAAAAAKP SDTGGGGSGG GAGSPGAQGT 250 260 270 280 290 300 | | | | | | KYPEHGNPAI LLMGSANGGP VVKTDSQQPL VWPAWVYCTR YSDRPSSPRT RKLKKKKNEK 310 320 330 340 350 360 | | | | | | EDKRPRTAFT AEQLQRLKAE FQANRYITEQ RRQTLAQELS LNESQIKIWF QNKRAKIKKA 370 380 390 | | | TGIKNGLALH LMAQGLYNHS TTTVQDKDES E Q05925 in FASTA format