UNSW Embryology
DNA- Human SRY
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Introduction Sry is the protein involved with male sex determination. The gene is located on the chromosome (which has a very low gene density). 3d Protein model swiss-protein
Other Formats: [FASTA Format] [Graphical View] Links:[1 medline link] [1 protein link] [103 nucleotide neighbors]  LOCUS HSSRY 2151 bp DNA PRI 26-JUN-1997 DEFINITION H.sapiens SRY gene. ACCESSION X53772 NID g36604 KEYWORDS sex determining region Y; Sry gene; testis-specific transcript; Y chromosome. SOURCE human. ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 2151) AUTHORS Palmer,M.S. TITLE Direct Submission JOURNAL Submitted (12-JUL-1990) Palmer M.S., Imperial Cancer Research Fund, Human Molecular Genetics Laboratory, P.O.Box 123, Lincoln's Inn Fields, London WC2A 3PX, UK REFERENCE 2 (bases 1 to 542; 543 to 902; 903 to 2151) AUTHORS Sinclair,A.H., Berta,P., Palmer,M.S., Hawkins,J.R., Griffiths,B.L., Smith,M.J., Foster,J.W., Frischauf,A.M., Lovell-Badge,R. and Goodfellow,P.N. TITLE A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif JOURNAL Nature 346 (6281), 240-244 (1990) MEDLINE 90326153 FEATURES Location/Qualifiers source 1..2151 /organism="Homo sapiens" /db_xref="taxon:9606" /chromosome="Y" /clone="pY53.3" /map="p1 region 1A1" gene 411..1025 /gene="SRY" CDS 411..1025 /gene="SRY" /codon_start=1 /db_xref="PID:g36605" /db_xref="SWISS-PROT:Q05066" /translation="MQSYASAMLSVFNSDDYSPAVQENIPALRRSSSFLCTESCNSKY QCETGENSKGNVQDRVKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLT EAEKWPFFQEAQKLQAMHREKYPNYKYRPRRKAKMLPKNCSLLPADPASVLCSEVQLD NRLYRDDCTKATHSRMEHQLGHLPPINAASSPQQRDRYSHWTKL" BASE COUNT 689 a 420 c 428 g 614 t ORIGIN 1 aagctttgtt tttttaaaga taacatacac atatattgat aatgataaac aattcatata 61 gctttttgtg tcctctcgtt ttgtgacata aaaggtcaat gaaaaaattg gcgattaagt 121 caaattcgca tttttcagga cagcagtaga gcagtcaggg aggcagatca gcagggcaag 181 tagtcaacgt tactgaatta ccatgttttg cttgagaatg aatacattgt cagggtacta 241 gggggtaggc tggttgggcg gggttgaggg ggtgttgagg gcggagaaat gcaagtttca 301 ttacaaaagt taacgtaaca aagaatctgg tagaagtgag ttttggatag taaaataagt 361 ttcgaactct ggcacctttc aattttgtcg cactctcctt gtttttgaca atgcaatcat 421 atgcttctgc tatgttaagc gtattcaaca gcgatgatta cagtccagct gtgcaagaga 481 atattcccgc tctccggaga agctcttcct tcctttgcac tgaaagctgt aactctaagt 541 atcagtgtga aacgggagaa aacagtaaag gcaacgtcca ggatagagtg aagcgaccca 601 tgaacgcatt catcgtgtgg tctcgcgatc agaggcgcaa gatggctcta gagaatccca 661 gaatgcgaaa ctcagagatc agcaagcagc tgggatacca gtggaaaatg cttactgaag 721 ccgaaaaatg gccattcttc caggaggcac agaaattaca ggccatgcac agagagaaat 781 acccgaatta taagtatcga cctcgtcgga aggcgaagat gctgccgaag aattgcagtt 841 tgcttcccgc agatcccgct tcggtactct gcagcgaagt gcaactggac aacaggttgt 901 acagggatga ctgtacgaaa gccacacact caagaatgga gcaccagcta ggccacttac 961 cgcccatcaa cgcagccagc tcaccgcagc aacgggaccg ctacagccac tggacaaagc 1021 tgtaggacaa tcgggtaaca ttggctacaa agacctacct agatgctcct ttttacgata 1081 acttacagcc ctcactttct tatgtttagt ttcaatattg ttttcttttc tctggctaat 1141 aaaggcctta ttcatttcag ttttactggt atttcatttt aaacttaatt tcaagacaag 1201 ttgtgtcaac acgattaaca tgcaaagaaa taagacatcc agaagtgagc ctgcctatgt 1261 ttgtggccgt cagagtacta acttgataca aacggacact gtggcttact ttaaatgctc 1321 taatgagaaa cacacttgaa aattgtacca aaaaaaatca cacttctata tgcagcgtgt 1381 taagcagtcc tctctagacc gtgtattcat tggtctttca gctactttgt acgtgtctat 1441 aaattgcagg taactaagga atggatatgt aagcaggatc aaacttgttt ctttctctcc 1501 ccttcacgct gtggaaaaaa ccagttttac ctccacttgc aattcagttc ctttactcca 1561 tataaatcca aacggttgac atttcctttc aactagttat aaaatgcctc tggtaaaaca 1621 aaatatttaa ttccttgtca tttttgtatc tctatgaaac ttatcatttt gcctttcttc 1681 tgaaaactat cttttaaaat ggcaatctac ttgtttccat ggcctattaa cttttaagcc 1741 tgtggaatga aaaatacaga attttcattc tcaacaggaa tgttgagaac gccgactacc 1801 cagattatgg agatggaagg gcgggggctg gtgacccaac tggtttaatt tgatgggatt 1861 taaataaaaa tgtaatgcca agacttcata aaatttgcac ataagctaaa gcaggaaact 1921 agaagtttac aaataactgt aaaccacagt ttaaagtata aattacaaat aaatttttct 1981 acaataaaaa taaatcaaaa gtcaaaatta atggtatgta tcaaagtcag ctttccaata 2041 tttcaaaact tttcagagac attaccttaa ataataaaac tcaaacacta aaagagtgta 2101 tattagagat ggatgtcatg tttctcaaag ttcagggttt aaaaaaagct t //
To see original entry from NCBI-Genbank
m.hill@unsw.edu.au Date Last Modified: 11/3/99 This site maintained by Dr M. Hill